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doi: 10.1016/j.smrv.2024.101996, 11
In kidney transplants, a slower decline in glomerular filtration rate, which measures kidney function, has been observed compared to other diabetes treatments
(PubMed) Why adding GIP matters In simplified terms: GLP-1R activation contributes to satiety and delayed gastric emptying GIPR activation can influence insulin secretion and broader metabolic signalling Clinical literature discusses tirzepatides dual activity and associated weight-loss outcomes, with adverse effects broadly similar to GLP-1RA class GI patterns

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