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Description

Metabolic adaptation

The mechanism of action involves several complementary pathways

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An extremely strong MCAS reaction in a second patient with long COVID and vaccine syndrome (plus antiphospholipid syndrome and major clot risk factors) caused her body to swell up so much that she had trouble eating

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Finally, we noted a significant increase in the AP firing frequency in response to GLP-1 (from 3.00.5 to 4.90.5 Hz, n =32, P =0.0004, paired t test) (Supplemental Fig