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Cytoplasmic domain mutational analysis and evidence for receptor homo-oligomerization

An athlete might not get the normal thirst cues during a long workout or race

Sterile mutants showed significant upregulation of immunity and fat metabolism genes To understand what could contribute to the lipid and lifespan changes in the sterile mutants at the molecular level, we next compared their gene expression profiles

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Allosteric modulation of G protein-coupled receptors

As cells in the distal end divide, some cells progress more proximally, away from the DTC, resulting in a decrease in GLP-1/Notch signaling levels, allowing for the activities of the GLD-1, GLD-2 and SCF PROM1 pathways to increase ((Wang et al., 2002