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A journey with platelet P-selectin: the molecular basis of granule secretion, signalling and cell adhesion

GLP-1 receptor agonists may possess certain neurotrophic properties that delay disease progression, Vijiaratnam and colleagues wrote

MariTide: This investigational drug from Amgen might only need to be injected once a month, which would be a massive win for convenience

GLP-1, or glucagon-like peptide-1, is a hormone produced in the gut that signals fullness to the brain, slows gastric emptying, and helps regulate blood sugar

However, previously, widespread shortages of injectable GLP-1s such as Ozempic and Wegovy disrupted care

Once the decision to switch is made, an individualised approach is recommended, based on considerations that include reimbursement requirements, treatment duration with (and dose of) previous GLP1RA, the patient's experience initiating the prior GLP1RA, any concomitant treatment and clinical characteristics