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Coats plus: a progressive familial syndrome of bilateral Coats disease, characteristic cerebral calcification, leukoencephalopathy, slow pre- and post-natal linear growth and defects of bone marrow and integument

Bassotti G, Usai Satta P, Bellini M

By combining careful medication assessment with empathetic communication and thorough documentation, clinicians can help patients transition toward the safest and most appropriate therapy available

Baseline assessment should include current thyroid status with TSH, free T4, and free T3 levels, documentation of Graves disease treatment history and current management, assessment of thyroid eye disease or other complications, cardiovascular evaluation including heart rate and rhythm (as both hyperthyroidism and GLP-1 receptor agonists can affect heart rate), and standard metabolic parameters including HbA1c, lipid profile, and renal function

The tirzepatide cohort also had a reduced need for pars plana vitrectomy, but it did not reach significance

However, the effectiveness of Topiramate can vary from person to person