glp-1 drugs side effects medication for diabetes and weight loss GLP-1 Medications for Weight Loss:

GLP-1RAs may also delay gastric emptying, potentially leading to retained gastric contents and aspiration risk

Thus, patients at high risk may benefit from complementary actions when being treated with a GLP-1RA/SGLT2i combination

article/pii/S2666776224002655 Yao, H., et al

Dulaglutide, a newer once-weekly GLP-1 receptor agonist, significantly increased heart rate (2.8 bpm, 95% CI: 1.5-4.2) compared with placebo at the dose of 1.5 mg [95]

The study found that participants who dieted and exercised achieved sustained weight loss on 5-milligram, 10-milligram, and 15-milligram doses of Zepbound

Ongoing research continues to refine our understanding of this potential complication, and clinicians should remain vigilant for emerging safety data while balancing the substantial metabolic benefits these medications provide for appropriate patients