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These observations, while compelling, are hypothesis-generating and require prospective validation before informing clinical use

In a recent study, researchers found that GLP-1RA medications such as Ozempic and Wegovy are associated with a higher risk of post-endoscopy aspiration pneumonia.

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Sites of protease/peptidase vulnerabilities in GLP-1 were removed by amino acid substitution and the peptide backbone was bis-lipidated to promote MEDI7219 reversible plasma protein binding without affecting potency