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This effect exceeds what has been observed with GLP-1-only agonists and is attributed to GIP receptor-mediated improvements in hepatic lipid metabolism and insulin sensitivity

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These exciting results indicate that orforglipron may be an effective, once-daily oral that can be taken without food or water restrictions. Orforglipron has also shown favorable outcomes for adults with Type 2 diabetes

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Wegovy is the brand approved for chronic weight management, while Ozempic is approved for type 2 diabetes

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