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In a multicenter, double-blind, randomized, placebo-controlled, event-driven superiority trial, designed to evaluate the efficacy and safety of 2.4 mg semaglutide in patients 45 years old with preexisting cardiovascular disease and a BMI 27 kg/m 2 but no history of diabetes, the trial randomly assigned 17,604 patients to receive semaglutide or placebo to determine whether semaglutide is superior to placebo in reducing cardiovascular events