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Macrophage Polarization GLP-1 agonists promote macrophages to change their inflammatory status from pro-inflammatory (M1) to anti-inflammatory (M2), which reduces inflammation in both the blood vessels and heart [43]

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After losing weight, "there's more cardiometabolic benefits, the blood pressure goes down further, the insulin goes down further, lipids improve further." Ahmad said the clinical trials will provide important insights for physicians treating patients, as well as for insurance companies and governments when determining whether to include weight loss drugs in their coverage