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Description
418,419,420 This activation holds the ability to modulate food consumption by reducing food intake and conveying signals of satiety to the brain
A challenge during the early development of GLP-1-based therapy was its short half-life in the circulation (approximately 2 min after i.v
mean BMI, 33.4 kg/m 2 ) and 7,122 did not use a GLP-1 (mean age, 37 years
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doi: 10.1056/NEJMc2109509
