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Polly says Piper became Polly, but the actual care experience stayed the same
In this process, platelet-derived THBS1 plays a key role in stimulating macrophages to differentiate into a highly proliferative M2 subtype, which contributes to renal fibrosis by secreting excessive extracellular matrix component
A 2025 preclinical study reported modulation of senescence-related pathways consistent with improved cellular function, though translation to human aging remains uncertain [17]
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It activates the same receptors in the body, which are present in the gut, pancreas, and brain
