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The ADA now recommends GLP1 RAs with proven benefit to slow CKD progression and reduce CV risk in people with type 2 diabetes

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Liraglutide was approved without a CVOT (Cardiovascular Outcome Trial) because authorities accepted the results from the LEADER study, designed for superiority

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As the use of GLP-1 drugs grow, some worry about widespread access.

The largest health insurer in the United States does not cover weight loss drugs
