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Both responses are typical

What Are Peptides for Weight Loss and How Do They Work
2022;doi:10.1056/NEJMoa2206038
In our Pavlovian experiment, semaglutide increased dopamine activity during reward, decreased food intake and reduced reward seeking
According to the Summary of Product Characteristics approved by the MHRA, injection site reactions are among the commonly reported adverse effects of Saxenda, though most are mild and transient