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GLP-1 medications like Ozempic (semaglutide) and Mounjaro (tirzepatide) mimic this hormone to help reduce hunger, increase fullness, and slow digestionall of which can support healthy weight loss

Medications such as semaglutide have shown promising results in clinical studies

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In order to further confirm the role of the gut-brain axis in this regulation, MG1363-pMG36e-GLP-1 was constructed, which could directly express GLP-1

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Following cerebral ischemia, the substantial release of various cytokines, chemokines and damage-associated molecular patterns (DAMPs) attributes to the activation and recruitment of neutrophils from the bone marrow, spleen, and peripheral circulation to the site of damage ( Table 2 )