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These spikes are temporary (lasting a couple of hours), but when combined with resistance training and adequate protein intake, they contribute to the overall anabolic environment your body needs to preserve muscle during weight loss

Nonalcoholic fatty liver disease (NAFLD), recently renamed metabolic dysfunction-associated steatotic liver disease (MASLD) affects ~70% of patients with type 2 diabetes (T2D), with ~20% showing signs of advanced liver fibrosis

These effects are primarily driven by the reduction of visceral adipose tissue but extend beyond mere weight loss: sympatholytic and -protective effects on the endothelium contribute to cardiovascular relief

In the context of implementing patient-centric holistic cardio-metabolic risk management as a priority, the choice of various combinations of antidiabetic agents should be individualized

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It results from the metabolic consequences due to a lack of insulin secretion or impaired insulin activity in diabetes leading to dysregulated pathophysiologic pathways resulting in excessive ketone body formation