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Signs and symptoms have included pruritus, rash, urticaria, angioedema, bronchospasm and anaphylaxis

However, the emergence of SGLT2 inhibitors, mineralocorticoid receptor antagonists, and GLP-1 receptor agonists has transformed the field

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68 demonstrated that exenatide combined with metformin resulted in an 86% ovulation rate, significantly higher than the 50% ovulation rate in the exenatide-only group and 29% in the metformin-only group

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