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doi: 10.7554/eLife.66170

It is the final chapter of a regulatory arc that was always going to end here

Its important that people are given advice on improving their diet and exercise, rather than relying solely on the drugs, as this may help them maintain good habits when they stop taking them. Dr Marie Spreckley, researcher in prevention of diabetes and related metabolic disorders in high-risk groups at the MRC Epidemiology Unit at the University of Cambridge, said it was important to distinguish between observed data and projections and longer-term follow-up studies are now needed to confirm whether this plateau occurs in routine practice

GLP-1 effects on blood pressure vary individually

It is also indicated to reduce the risk of stroke, heart attack, and death in patients with diabetes and cardiovascular disease, says Katherine H

Gradual titration is the key to sticking with the therapy long enough to see results