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Conclusion GLP1 agonists, in particular, semaglutide and tirzepatide are remarkably effective weight loss drugs that have demonstrated a myriad of positive health benefits in obese and overweight patients, including, most notably, improved overall survival

2,48 Concern about the risk of pancreatitis increased after GLP-1 receptor agonist indications for use expanded to include cardiovascular and renal protection, obesity and metabolic dysfunctionassociated fatty liver disease (MAFLD

2016 Apr;229(1):1-12

The World Obesity Federation states that nearly 2.8 billion people worldwide are affected by obesity 1

Additionally, production and supply constraints, including high manufacturing costs and limited scalability, pose significant barriers