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Preclinical work also points to applications in reproductive health (e.g., PCOS-related fertility improvements) and oncology, where observational studies link GLP-1 use to lower risks of obesity-related cancers

Tirzepatide use increased over time, consistent with broader population trends (15)

Even among large firms that do not cover GLP-1s for weight loss, 45% say that doing so is very important or somewhat important for employees` satisfaction

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For patients taking GLP-1 agonists, the mechanism that helps regulate appetite and glucose control can also slow gastric emptying, contributing to constipation