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Chen and R

This multi-receptor strategy sets it apart from previous generations of weight loss drugs by addressing not just hunger and insulin regulation, but also energy expenditure and fat oxidation

[DOI] [PMC free article] [PubMed] [Google Scholar] Lau J

After 28 days, potency begins to decline and bacterial contamination risk increases beyond acceptable levels

Some people also experience headaches, increased infections, rapid heart rate, dizziness, and indigestion

These data suggest that GLP-1RAs may have unwanted oncogenic effects on receptor-positive NET subtypes (e.g., duodenal, gastric, and pancreatic NETs) and are less likely to affect NENs lacking the receptor (e.g., thyroid and ileal NETs)