can you drink alcohol on glp 1 while using semaglutide GLP-1 and alcohol — what to keep in mind GLP-1 & Alcohol: What Happens
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In the tirzepatide SURMOUNT-1 body-composition substudy, 26 percent of the weight people lost was lean mass, and in that same study, people in the placebo group who lost weight without any drug lost 25 percent of theirs as lean mass (Look et al., 2025)
[DOI] [PMC free article] [PubMed] [Google Scholar] 27.Tseng P.-L., Chung T.-L., Lee C.-H

While not approved specifically for weight loss, clinical trials showed average weight reduction of 3-5% of body weight, making it the least potent option in this category for weight management

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doi: 10.1056/NEJMoa2107519 [DOI] [PubMed] [Google Scholar] 30.Frias JP, Nauck MA, Van J, et al
