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Experiments in rodents show that stimulating central GLP-1 signaling suppresses eating, alters food-seeking behavior, and engages stress-related pathways

GLP-1 Receptor Agonists Show Modest Reduction in HR+ Breast Cancer Incidence Cancer Network Staff Ariana Pelosci , Tim Cortese , Nicole Canfora Lupo GLP-1 receptor agonist use was tied to reduced HR+/HER2 breast cancer incidence and improved overall survival in nondiabetic women with elevated BMI

Sze L, Purtell L, Jenkins A, Loughnan G, Smith E, Herzog H, et al

[DOI] [PubMed] [Google Scholar] 22.Burnier M Blockade of the Renin-Angiotensin System and the Risk of Acute Kidney Injury

Consequently, more consumers are preferring to consume nutrient-rich, controlled-calorie, and easily digestible packaged food and beverages, thus pushing companies to develop GLP-1 friendly items

These divergent findings highlight that the net effect on tumorigenesis is modulated by the interplay among tumor cell-intrinsic factors, host systemic metabolism and pharmacological characteristics