GLP-1 Fatigue
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Description
They improve blood sugar
[DOI] [PMC free article] [PubMed] [Google Scholar] 95.Sanyal AJ, Kaplan LM, Frias JP, et al
Heres the important context: weight loss on any intervention, including a GLP-1 medication, is almost never a smooth downward line
In retatrutide trials specifically, starting at 4 mg instead of 2 mg nearly doubled early GI symptom rates
Liver fat content decreased by 44% in a subset of participants who underwent MRI imaging
For other nutrients, like B12, absorption through the skin is trickier and they may not work as well as advertised
