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Foods that make GLP-1 constipation worse Some foods actively slow transit or harden stool
Cosmos Study December 16, 2025 Dual-Team Study Team A:Kersten Bartelt, RNNicholas Volker Team B:Tony Dunnigan, MDEric Barkley Key Findings Among patients with type 2 diabetes, GLP-1 use was associated with a 32% lower fracture risk for those with either osteopenia or osteoporosis

Andres Acosta, an obesity expert at Mayo Clinic who was not involved in the study, said that not one, but many genetic variants contribute to the differences in how people respond to these drugs

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Because these hormonal pathways can be tied to numerous bodily processes, researchers are now trying to study what else GLP-1 analogs could potentially treat

The cardiovascular outcomes suggest that GLP-1 therapy offers systemic health benefits beyond simple calorie restriction, making these medications attractive for overall metabolic health even in the absence of diabetes