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When taken on an empty stomach, peptides can be absorbed more efficiently into the bloodstream as they are less likely to compete with other nutrients or substances in the digestive system

Sitagliptin improved glucose assimilation in detriment of fatty-acid utilization in experimental type-II diabetes: role of GLP-1 isoforms in Glut4 receptor trafficking

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Strategies to reduce side effects, such as slow dose escalation, unfortunately do not fully mitigate nausea, vomiting, and gastrointestinal (GI) distress, which are the primary reasons for treatment discontinuation ( 5 )

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