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Nervous system Very common (10% or more): Dysesthesia (up to 22%), headache (up to 17%) Common (1% to 10%): Dizziness, dysgeusia Uncommon (0.1% to 1%): Syncope Postmarketing reports : Headache, dizziness, dysgeusia, dysesthesia Dysesthesia included allodynia, burning sensation, hyperesthesia, hyperpathia, pain of skin, paresthesia, sensitive skin, skin burning sensation, skin discomfort, and skin sensitization

Physical activity recommendations include at least 150 minutes of moderate-intensity aerobic exercise weekly, combined with resistance training two to three times per week, individualized based on cardiovascular status and physical limitations

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The clinical trials and post-marketing surveillance that inform the official prescribing information approved by the Medicines and Healthcare products Regulatory Agency (MHRA) and European Medicines Agency (EMA) have not established chest pain as a recognised side effect of this medication