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As with any medication, side effects like nausea, mild gastrointestinal discomfort, or loss of appetite may occur initially but typically lessen over time

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[DOI] [PubMed] [Google Scholar] 39.Lincoff AM, Brown-Frandsen K, Colhoun HM, et al

Second, retatrutide has reached closer to steady-state concentration in the blood at the initial dose level
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