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Campbell JE, Drucker DJ (2013) Pharmacology, physiology, and mechanisms of incretin hormone action

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2,17-22 During this investigation, increased CV mortality was found in patients assigned to the first-generation sulfonylurea tolbutamide

doi: 10.1016/j.cmet.2019.07.013

Even a 15 to 20 minute walk after meals can meaningfully improve gut motility and reduce constipation
