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In one trial, patients who took Wegovy lost an average of 14.9% of their body weight compared to 2.4% loss for patients on the placebo, according to Novo Nordisk

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Observational studies are included to provide evidence on effectiveness in broader, more heterogeneous real-world populations, to capture longer-term outcomes beyond typical RCT durations, and to assess safety signals that may be too rare to detect in RCTs

However, B12 is not directly involved in fat metabolism the way L-carnitine is
