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Description
Murine primary chondrocytes were isolated from the knee articular cartilage of 6 days-old C57Bl/6 mice as previously described 67
It is not medical advice and should not be used to make decisions about managing a diagnosed health condition
The cells are suitable for use in high-throughput systems to screen for inhibitors or agonists
In clinical trial protocols, the drug is initiated at a low dose and titrated gradually upwards to minimise gastrointestinal side effects
This metabolic detourvia the mouth, rather than the gutcould make a significant difference
Both IR D707A/ and IR / mice exhibited marked cytoplasmic vacuolization of hepatocytes (Fig
