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Description
Each approach hit a ceiling because metabolic homeostasis is a multi-variable system
Additionally, only a few mouse model studies of exendin-4, another GLP-1 RA, were identified in the review to examine the possibility of transfer across the placenta to the offspring
Novel development of a co-formulation of insulin and amylin
They work through different biological mechanisms and are not interchangeable
Many countries factor WHO guidelines into their health policies
Proc Natl Acad Sci U S A (2014) 111(13):E125663
