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Should tirzepatide be used in patients with active hyperthyroidism, and what is the recommended management?

Glucagon-like-peptide-1 (GLP-1) targets areas of the brain that regulate appetite

This also had an impact on sensitivity analysis 4, which adjusted for baseline HbA1c and body weight in patients on metformin in SURPASS2 and patients on metformin with or without a sulphonylurea in SUSTAIN FORTE

Analyses were performed to examine the rate of adverse CVEs using Cox proportional hazards models

Its important to remember that individual responses may vary, and adjustments might be necessary, which highlights the value of personalized treatment plans

This is a particular concern with CKD because malnutrition is a recognised complication of kidney disease and worsens long-term outcomes