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Similarly, the substudy of the obesity phase 2 trial showed clear promise for retatrutide in the treatment of MASLD [47], and through its GCG receptor agonism, retatrutide may offer benefits beyond WL, through weight-independent metabolic effects at the liver [40]

Preliminary clinical trials show that exenatide-treated patients have a mean improvement at 12 months on the MDS-UPDRS of 2.7 points, compared with a mean decline of 2.2 points in control patients [193]

GIP/GLP-1 RAs Currently, tirzepatide is the only GIP/GLP-1 RA developed and approved for clinical use in Japan (Fig

It often occurs in the morning and/or after longer periods without eating

Upholds peoples safety, health and the environment

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