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NAc, nucleus accumbens

GLP-1R triggers various intracellular signaling pathways, such as the cAMP/PKA and PI3K/Akt pathways, by binding to endogenous GLP-1 or exogenous agonists, resulting in the enhancement of insulin secretion, inhibition of glucagon secretion, as well as anti-inflammatory and antioxidant stress response

The test identifies genetic variants in appetite-control pathways (GLP1R, GIPR, FTO, MC4R) that predict how strongly you'll respond to semaglutide and how vigorously your body resists weight loss

Based on the pattern of hair loss and the clinical findings from the hair examination, the condition was consistent with a diagnosis of alopecia areata