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The metabolic improvements extend beyond weight loss

During clinical trials, people receiving Zepbound lost up to nearly 21% of their starting body weight over 72 weeks (about 16.5 months)
This aligns with human tolerance data by Han et al (2018)

Early diagnosis and treatment are important for dealing with gastroparesis well and avoiding problems. A woman filed a lawsuit against the drug makers for Ozempic and Mounjaro after experiencing severe gastrointestinal events, including gastroparesis, also known as stomach paralysis
Decreased intake of a liquid diet in nonfood-deprived rats following intra-PVN injections of GLP-1 (736) amide

It was draining to say the least
