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The GI adverse event profile at 12 mg was meaningfully higher

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Alcohol Drinking alcohol while taking atorvastatin can increase the risk of liver problems

Actual Medication Cost Per Dose Approximate Compounding Costs: While providers dont break this down, approximate pharmaceutical costs: Per Dose (Wholesale to Pharmacy): 2.5 mg dose: ~$15-25 5 mg dose: ~$25-40 7.5 mg dose: ~$35-55 10 mg dose: ~$45-70 12.5 mg dose: ~$55-85 15 mg dose: ~$65-100 Monthly Medication Cost (4 doses): 2.5 mg weekly: ~$60-100/month 5 mg weekly: ~$100-160/month 7.5 mg weekly: ~$140-220/month 10 mg weekly: ~$180-280/month 12.5 mg weekly: ~$220-340/month 15 mg weekly: ~$260-400/month Additional costs for providers: Medical consultation/oversight: ~$50-100/month allocated Supplies (syringes, sharps, pads): ~$10-20/month Shipping and handling: ~$15-25/month Customer support and operations: ~$30-50/month Platform/technology costs: ~$20-40/month Total provider cost: ~$250-400/month at maximum doses Provider pricing of $349-$699/month represents reasonable to premium margins over actual costs

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[DOI] [PubMed] [Google Scholar] 27.Orforglipron, an oral non-peptide glucagon-like peptide-1 receptor agonist, improves markers of -cell function and insulin sensitivity in type 2 diabetes