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In humans, the incretins GLP-1 and GIP as well as the GLP-1RA and GLP-1R/GIPR dual agonists have demonstrated antiinflammatory effects (65, 85)

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Whats the difference between semaglutide and GLP-1

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It emerges from two converging threads: 1

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At 5 mg/ml concentration: 2.5 mg = 0.5 ml = 50 units

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Several RCTs including SAVORTIMI 53 (saxagliptin) [52], EXAMINE (alogliptin) [53], and TECOS (sitagliptin) [54] have shown that DPP4 inhibitors did not significantly reduce stroke risk [1]

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