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Theoretically, the delayed gastric emptying induced by GLP-1 receptor agonists means that stomach contents remain in the stomach for extended periods

Dose reductions of insulin or sulfonylureas may be needed to prevent hypoglycaemia

Instead of waiting until you feel hungry, try planning small, balanced meals or snacks at regular intervals throughout the day

And if a patient meets their goalsloses weight, improves blood sugar, blood pressure, or cholesterolwe may even de-escalate therapy by lowering the semaglutide dose or switching to liraglutide to prevent excess weight loss, which can come at the expense of muscle mass. Overall, switching works best when its intentional and coordinated with your physician

Those gains have come largely before oral GLP-1 medications have achieved widespread availability

Starting Tirzepatide can feel hopeful and scary at once: you see real weight loss, but you also read about concerning side effects