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Description
Free fatty acids act on receptors including GPR 43, GPR119 and GPR 120, and FFAR (29, 51, 113), and proteins may act through the Ca 2+ sensing receptor (CaSR) which responds to amino acids (24) or the peptide transporter PepT1 (69)

That's how studies fail

Some patients may continue medication long term, some may adjust the dose, and others may transition to a different maintenance plan

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Fortunately, trials suggest a lower dose might mitigate side effects satisfactorily

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