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Prasad-Reddy, L., & Isaacs, D

The AACE/ACE, in contrast to the ADA, provides several monotherapy options that are recommended in the following order according to the strength of each recommendation: metformin, GLP-1 receptor agonist, SGLT-2 inhibitor, DPP-4 inhibitor, thiazolidinedione, -glucosidase inhibitor, and an insulin secretagogue (a sulfonylurea or meglitinide)

The Journal of Pediatrics

Secondary analysis of renal end points in a cardiovascular safety trial of a DPP-4 inhibitor in patients with T2DM at high cardiovascular risk, showing that saxagliptin reduces albuminuria in a glucose-independent manner

Several FDA-approved weight loss medications work through completely different mechanisms

GLP-1 RAs help people lose weight better than lifestyle changes alone, and they work better than other types of weight-loss medication