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Moreover, given that there are now millions of patient-years of clinical experience with DPP-4 inhibitors since they were given regulatory approval in 2006, their benign, placebo-like side effect profile (39) also suggests that the number of physiologically relevant substrates is likely to be limited
Long-Term Safety: Although GLP-1 medications have demonstrated efficacy and safety in clinical trials, their long-term safety profile is still being evaluated

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Nakane, T., Kimanius, D., Lindahl, E

doi: 10.1136/bmj.b496, 106 NeratziS.SergentanisT.TsitsikaA

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