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Maximizing the value of GLP-1RAs and next-generation pleiotropic drugs will demand effective navigation of data management and analysis, deals and licensing, regulatory exclusivity, and strategic patent prosecution
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Future efforts to identify and develop GPR17 antagonists and inverse agonists are expected to be fruitful for enhancing GLP-1 secretion and improving glucose homeostasis
Akkermansia muciniphila (4), often called the "guardian of the gut barrier," has emerged as a key player in GLP-1 production
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