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The authors discuss the preclinical literature and emerging clinical evidence that support the rationale for investigating the use of glucagon-like peptide-1 receptor agonists to prevent and treat several neurodegenerative diseases of aging, with a focus on Alzheimers disease.

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recently presented detailed Phase 2b results for berobenatide (PF3944), an investigational once-weekly and once-monthly GLP-1 receptor agonist, showing proof of concept for meaningful weight loss with low gastrointestinal side effects across obesity and type 2 diabetes populations

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Sergey Terushkin, MD achieved incredible results using GLP-1 medications Semaglutide (Ozempic, Wegovy) and Tirzepatide (Mounjaro, Zepbound) or through gastric sleeve and revision surgery