semaglutide found in nature A trial emulation Medicine shows that treatment with and tirzepatide showed similar levels of benefit on cardiovascular outcomes in people at elevated cardiovascular risk with obesity and diabetes. Link A Multidisciplinary Perspective on Semaglutide

RESULTS Among 11,362,626 patients in our database, 122,008 met the inclusion criteria (mean age: 75.0 12.3 years, 59.3% female)

STEP-1 took 1961 adults with a BMI 30 (or 27 in people with 1 weight-related coexisting condition) without T2D and demonstrated mean weight reduction of 14.8% in participants taking semaglutide 2.4 mg weekly (vs

Concomitant CV therapies could be adjusted, at the discretion of the investigator, to ensure participants were treated according to the current standard of care for patients with established CV disease

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At baseline, there were no statistically significant differences between the two groups regarding weight, height, or BMI