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Clinical studies have not established decreased libido as an official side effect, but the emerging case report literature and proposed neurochemical mechanisms suggest it occurs in a subset of women

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Ongoing mechanistic and clinical research will determine whether these agents possess inherent reproductive benefits or primarily facilitate fertility through systemic metabolic restoration

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Some people also report slightly stronger initial nausea when starting or increasing doses, as the medication enters the bloodstream more directly

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It should be noted that the the Food and Drug Administration has addressed concerns about unapproved GLP-1 drugs used for weight loss

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Subcutaneous adipose tissue: implications in dermatological diseases and beyond

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J.FrancisD.OliverN.et al (2018)

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