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ELIXA trial included patients with recent cardiovascular event (patients with acute coronary syndrome 180 days before randomization), and although there was no benefit in MACE reduction in lixisenatide treated patients compared to placebo, results revealed cardiovascular safety of lixisenatide in this specific high risk population (38, 40)

These may include nausea, decreased appetite, vomiting, constipation, diarrhea, bloating, or abdominal discomfort

Everythingfrom how they are administered to how long their effects lastdepends on the type of GLP-1 molecule used

Liraglutide for the treatment of type 2 diabetes: a clinical update

Role of GLP-2 in inflammatory regulation in IBD Administration of teduglutide, a GLP-2 analog to mice with DSS-induced colitis, resulted in a significantly greater small bowel and colon weight and length compared with untreated mice

Beyond weight management, retatrutide exhibits profound metabolic benefits that extend to cardiovascular health and glycemic control