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Additionally, the phase 2 MOMENTUM clinical trial of pemvidutide (a dual GLP-1/GCG agonist) showed that only 21.9% of WL was attributable to reductions in lean mass at 48 weeks (overall WL 10.315.6% across doses) [64]
10.1101/gad.9.12.1491 41 JungkampA.-C.StoeckiusM.MecenasD.GrnD.MastrobuoniG.KempaS.et al (2011)
Astrup, et al.66, utilizaron la liraglutida para el tratamiento de la obesidad en 564 sujetos con ndice de masa corporal entre 30 y 40kg/m2, los cuales fueron asignados al azar a tres brazos: la liraglutida (cuatro dosis 1,2, 1,8, 2,8, 3mg), el orlistat o el placebo y los tres grupos recibieron una dieta con moderada restriccin calrica
Changes in mood can occur from many sources, including weight loss, so further research is necessary to delineate the actual mechanism, pointed out Ali
N., Wharton, S., Connery, L., Alves, B., & Stefanski, A
