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April 9, 2024 One of the first studies to attempt to treat early-stageheart failurein patients with Type 2 diabetes did not meet its primary endpoint, but a preplanned subgroup analysis found a statistically significant effect of treatment in patients who were not takingSGLT2inhibitors or GLP-1 RAs, which are antidiabetic medications that also have benefits for the heart

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Clinicians must prioritize robust preconception counseling and switch to preferred agents like insulin for pregnant patients.