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Description
Most trials included in the analysis were designed with TBWL as the primary endpoint

Strategies to enhance the tolerability of GLP-1-based therapy might include identification of agents that stimulate release of endogenous GLP-1 from intestinal L-cells, potentially accompanied by fewer adverse effects

In general, medical weight loss may not be suitable for those who are pregnant, breastfeeding, or planning to become pregnant, or for individuals with a history of certain thyroid conditions (such as medullary thyroid cancer or MEN 2), pancreatitis, or significant kidney or liver disease

Conclusion Employers must consider many factors, including costs, compliance, and employee expectations, when determining whether to offer GLP-1 coverage under the health plans they sponsor

Adding to what we know about GLP-1 medications and colorectal cancer risk, Cuomo is the lead author of a new study recently published in the journal Cancer Investigation, which found that GLP-1 medications may help lower mortality risk for people who have colon cancer, a type of colorectal cancer

Increased heart rate Some people develop an elevated resting heart rate on semaglutide
